Subserous uterine myoma in postmenopausal women

18 september 2018
Федина Татьяна Леонидовна
district gynecologist, gynecologist-surgeon (sod)

Patient A. is 66 years old.

The patient came to the clinic on January 13, 2017 with an established diagnosis: clear cell endometrial cancer.

Medical history:

·         menstruation from 13 years old, established immediately, regular (after 28 to 5 days), moderate, painless. Postmenopause from 53 years old;

·         within 2 years periodically consulted a gynecologist at the place of residence with complaints of a single scanty vaginal discharge.

Medical history.

According to her, according to the ultrasound examination, the endometrium corresponded to the period of menopause and additional examination was not carried out.

Since November 2016, she has noted the appearance of moderate bleeding from the vagina, in connection with which hysteroscopy and separate scraping of the uterine cavity and cervical canal were performed in the clinic at the place of residence. According to the histological examination, the diagnosis was made: squamous cell carcinoma of the endometrium.

From the past diseases: hypertension stage 2, risk of 3 NK stage 1. Atherosclerosis of the aorta, aortic valve, small liver cysts, kidney cysts, superficial gastritis, duodenitis, catarrhal colitis, dolichosigma, chronic hemorrhoids.


On examination, the diagnosis was confirmed. Histological response: clear cell adenocarcinoma (high grade) with full-thickness extension of endometrial fragments against the background of endometrial atrophy.

According to the ultrasound examination of the pelvic organs, the endometrium is 1.7 mm, linear, the basal layer is indistinct, signs of subserous uterine fibroids and evolutive changes in the pelvic organs.

According to PET / CT, there were no signs of a pathological metabolic active process, including in the uterus. Myomatous node in the body of the uterus.

After the oncological consultation, surgical treatment was performed in the volume - extirpation of the uterus with appendages with pelvic lymphadenectomy.


According to the final histological examination, the diagnosis: clear cell adenocarcinoma (high grade) (the tumor is limited to the endometrium).

Against the background of cystic atrophy of the endometrium without signs of invasive growth in the myometrium. Multiple leiomyoma of the uterus with dystrophic changes and calcification of the larger of the nodes. Isthmus, cervix without tumor growth. Sclerotic changes in the tubes. In the ovaries on the right, there is a simple serous cyst. Brenner's tumor in the left ovary. Lymph nodes without tumor growth. Immunohistochemical study: PR expression is absent in tumor cells.

Final diagnosis : clear cell endometrial cancer 1A st (T1 N0 M0).

In the postoperative period, laboratory signs of hypercoagulability were noted, despite the prescribed prophylaxis of thromboembolic complications in the early postoperative period, which is typical for this tumor. The postoperative period was uneventful. The patient was discharged from the clinic on the 6th day with full recovery.

The oncologist's observation is recommended 2 times a year.